Cancer Treatment and Research During the COVID-19 Pandemic: Experience of the First 6 Months.
Identifieur interne : 001410 ( Main/Exploration ); précédent : 001409; suivant : 001411Cancer Treatment and Research During the COVID-19 Pandemic: Experience of the First 6 Months.
Auteurs : Bego A De Las Heras [États-Unis, Espagne] ; Kamal S. Saini [États-Unis, Royaume-Uni] ; Frances Boyle [Australie] ; Felipe Ades [Brésil] ; Evandro De Azambuja [Belgique] ; Ivana Bozovic-Spasojevic [Serbie] ; Marco Romano [États-Unis] ; Marta Capelan [Espagne] ; Rajeev Prasad [Royaume-Uni] ; Pugazhenthi Pattu [Royaume-Uni] ; Christophe Massard [France] ; Chia Portera [États-Unis] ; Monika Lamba Saini [Belgique] ; Brajendra Prasad Singh [Inde] ; Ramachandran Venkitaraman [Royaume-Uni] ; Richard Mcnally [États-Unis] ; Manuela Leone [États-Unis] ; Enrique Grande [Espagne] ; Sudeep Gupta [Inde]Source :
- Oncology and therapy [ 2366-1089 ] ; 2020.
Abstract
The coronavirus disease-2019 (COVID-19) pandemic has had a significant impact on patients with underlying malignancy. In this article, we summarize emerging data related to patients with cancer and COVID-19. Among patients with COVID-19, a higher proportion have an underlying diagnosis of cancer than seen in the general population. Also, patients with malignancy are likely to be more vulnerable than the general population to contracting COVID-19. Mortality is significantly higher in patients with both cancer and COVID-19 compared with the overall COVID-19-positive population. The early months of the pandemic saw a decrease in cancer screening and diagnosis, as well as postponement of standard treatments, which could lead to excess deaths from cancer in the future.
DOI: 10.1007/s40487-020-00124-2
PubMed: 32749634
PubMed Central: PMC7402077
Affiliations:
- Australie, Belgique, Brésil, Espagne, France, Inde, Royaume-Uni, Serbie, États-Unis
- Catalogne, Communauté de Madrid, New Jersey, Nouvelle-Galles du Sud, Région de Bruxelles-Capitale, État de São Paulo
- Barcelone, Bruxelles, Madrid, Sydney, São Paulo, Villejuif
- Université libre de Bruxelles
Links toward previous steps (curation, corpus...)
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Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Université Libre de Bruxelles (U.L.B.), Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Université Libre de Bruxelles (U.L.B.), Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName><orgName type="university">Université libre de Bruxelles</orgName></affiliation></author><author><name sortKey="Bozovic Spasojevic, Ivana" sort="Bozovic Spasojevic, Ivana" uniqKey="Bozovic Spasojevic I" first="Ivana" last="Bozovic-Spasojevic">Ivana Bozovic-Spasojevic</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Institute for Oncology and Radiology of Serbia, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Romano, Marco" sort="Romano, Marco" uniqKey="Romano M" first="Marco" last="Romano">Marco Romano</name><affiliation wicri:level="2"><nlm:affiliation>Covance Inc., Princeton, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Covance Inc., Princeton, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Capelan, Marta" sort="Capelan, Marta" uniqKey="Capelan M" first="Marta" last="Capelan">Marta Capelan</name><affiliation wicri:level="3"><nlm:affiliation>Vall d'Hebron University Hospital, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Vall d'Hebron University Hospital, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Prasad, Rajeev" sort="Prasad, Rajeev" uniqKey="Prasad R" first="Rajeev" last="Prasad">Rajeev Prasad</name><affiliation wicri:level="1"><nlm:affiliation>Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Barking, Havering and Redbridge University Hospitals NHS Trust, Romford</wicri:regionArea><wicri:noRegion>Romford</wicri:noRegion></affiliation></author><author><name sortKey="Pattu, Pugazhenthi" sort="Pattu, Pugazhenthi" uniqKey="Pattu P" first="Pugazhenthi" last="Pattu">Pugazhenthi Pattu</name><affiliation wicri:level="1"><nlm:affiliation>East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>East Suffolk and North Essex NHS Foundation Trust, Ipswich</wicri:regionArea><wicri:noRegion>Ipswich</wicri:noRegion></affiliation></author><author><name sortKey="Massard, Christophe" sort="Massard, Christophe" uniqKey="Massard C" first="Christophe" last="Massard">Christophe Massard</name><affiliation wicri:level="3"><nlm:affiliation>Gustave Roussy, Université Paris-Saclay, Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Gustave Roussy, Université Paris-Saclay, Villejuif</wicri:regionArea><placeName><settlement type="city">Villejuif</settlement></placeName></affiliation></author><author><name sortKey="Portera, Chia" sort="Portera, Chia" uniqKey="Portera C" first="Chia" last="Portera">Chia Portera</name><affiliation wicri:level="2"><nlm:affiliation>Covance Inc., Princeton, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Covance Inc., Princeton, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Saini, Monika Lamba" sort="Saini, Monika Lamba" uniqKey="Saini M" first="Monika Lamba" last="Saini">Monika Lamba Saini</name><affiliation wicri:level="1"><nlm:affiliation>HistoGeneX, Antwerp, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>HistoGeneX, Antwerp</wicri:regionArea><wicri:noRegion>Antwerp</wicri:noRegion></affiliation></author><author><name sortKey="Singh, Brajendra Prasad" sort="Singh, Brajendra Prasad" uniqKey="Singh B" first="Brajendra Prasad" last="Singh">Brajendra Prasad Singh</name><affiliation wicri:level="1"><nlm:affiliation>Max Smart Super Speciality Hospital, Saket, New Delhi, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Max Smart Super Speciality Hospital, Saket, New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author><author><name sortKey="Venkitaraman, Ramachandran" sort="Venkitaraman, Ramachandran" uniqKey="Venkitaraman R" first="Ramachandran" last="Venkitaraman">Ramachandran Venkitaraman</name><affiliation wicri:level="1"><nlm:affiliation>East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>East Suffolk and North Essex NHS Foundation Trust, Ipswich</wicri:regionArea><wicri:noRegion>Ipswich</wicri:noRegion></affiliation></author><author><name sortKey="Mcnally, Richard" sort="Mcnally, Richard" uniqKey="Mcnally R" first="Richard" last="Mcnally">Richard Mcnally</name><affiliation wicri:level="2"><nlm:affiliation>Covance Inc., Princeton, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Covance Inc., Princeton, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Leone, Manuela" sort="Leone, Manuela" uniqKey="Leone M" first="Manuela" last="Leone">Manuela Leone</name><affiliation wicri:level="2"><nlm:affiliation>Covance Inc., Princeton, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Covance Inc., Princeton, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Grande, Enrique" sort="Grande, Enrique" uniqKey="Grande E" first="Enrique" last="Grande">Enrique Grande</name><affiliation wicri:level="3"><nlm:affiliation>MD Anderson Cancer Center Madrid, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>MD Anderson Cancer Center Madrid, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Gupta, Sudeep" sort="Gupta, Sudeep" uniqKey="Gupta S" first="Sudeep" last="Gupta">Sudeep Gupta</name><affiliation wicri:level="1"><nlm:affiliation>Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Tata Memorial Centre, Homi Bhabha National Institute, Mumbai</wicri:regionArea><wicri:noRegion>Mumbai</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32749634</idno><idno type="pmid">32749634</idno><idno type="doi">10.1007/s40487-020-00124-2</idno><idno type="pmc">PMC7402077</idno><idno type="wicri:Area/Main/Corpus">000739</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000739</idno><idno type="wicri:Area/Main/Curation">000739</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000739</idno><idno type="wicri:Area/Main/Exploration">000739</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Cancer Treatment and Research During the COVID-19 Pandemic: Experience of the First 6 Months.</title><author><name sortKey="De Las Heras, Bego A" sort="De Las Heras, Bego A" uniqKey="De Las Heras B" first="Bego A" last="De Las Heras">Bego A De Las Heras</name><affiliation wicri:level="2"><nlm:affiliation>Covance Inc., Princeton, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Covance Inc., Princeton, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Madrid Medical Doctors Association, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Madrid Medical Doctors Association, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Saini, Kamal S" sort="Saini, Kamal S" uniqKey="Saini K" first="Kamal S" last="Saini">Kamal S. Saini</name><affiliation wicri:level="2"><nlm:affiliation>Covance Inc., Princeton, NJ, USA. kamalveer.saini@covance.com.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Covance Inc., Princeton, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK. kamalveer.saini@covance.com.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>East Suffolk and North Essex NHS Foundation Trust, Ipswich</wicri:regionArea><wicri:noRegion>Ipswich</wicri:noRegion></affiliation></author><author><name sortKey="Boyle, Frances" sort="Boyle, Frances" uniqKey="Boyle F" first="Frances" last="Boyle">Frances Boyle</name><affiliation wicri:level="3"><nlm:affiliation>Mater Hospital, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Mater Hospital, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Ades, Felipe" sort="Ades, Felipe" uniqKey="Ades F" first="Felipe" last="Ades">Felipe Ades</name><affiliation wicri:level="3"><nlm:affiliation>Hospital Alemão Oswaldo Cruz, São Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Hospital Alemão Oswaldo Cruz, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="De Azambuja, Evandro" sort="De Azambuja, Evandro" uniqKey="De Azambuja E" first="Evandro" last="De Azambuja">Evandro De Azambuja</name><affiliation wicri:level="3"><nlm:affiliation>Institut Jules Bordet, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Institut Jules Bordet, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Université Libre de Bruxelles (U.L.B.), Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Université Libre de Bruxelles (U.L.B.), Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName><orgName type="university">Université libre de Bruxelles</orgName></affiliation></author><author><name sortKey="Bozovic Spasojevic, Ivana" sort="Bozovic Spasojevic, Ivana" uniqKey="Bozovic Spasojevic I" first="Ivana" last="Bozovic-Spasojevic">Ivana Bozovic-Spasojevic</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.</nlm:affiliation><country xml:lang="fr">Serbie</country><wicri:regionArea>Institute for Oncology and Radiology of Serbia, Belgrade</wicri:regionArea><wicri:noRegion>Belgrade</wicri:noRegion></affiliation></author><author><name sortKey="Romano, Marco" sort="Romano, Marco" uniqKey="Romano M" first="Marco" last="Romano">Marco Romano</name><affiliation wicri:level="2"><nlm:affiliation>Covance Inc., Princeton, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Covance Inc., Princeton, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Capelan, Marta" sort="Capelan, Marta" uniqKey="Capelan M" first="Marta" last="Capelan">Marta Capelan</name><affiliation wicri:level="3"><nlm:affiliation>Vall d'Hebron University Hospital, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Vall d'Hebron University Hospital, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Prasad, Rajeev" sort="Prasad, Rajeev" uniqKey="Prasad R" first="Rajeev" last="Prasad">Rajeev Prasad</name><affiliation wicri:level="1"><nlm:affiliation>Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Barking, Havering and Redbridge University Hospitals NHS Trust, Romford</wicri:regionArea><wicri:noRegion>Romford</wicri:noRegion></affiliation></author><author><name sortKey="Pattu, Pugazhenthi" sort="Pattu, Pugazhenthi" uniqKey="Pattu P" first="Pugazhenthi" last="Pattu">Pugazhenthi Pattu</name><affiliation wicri:level="1"><nlm:affiliation>East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>East Suffolk and North Essex NHS Foundation Trust, Ipswich</wicri:regionArea><wicri:noRegion>Ipswich</wicri:noRegion></affiliation></author><author><name sortKey="Massard, Christophe" sort="Massard, Christophe" uniqKey="Massard C" first="Christophe" last="Massard">Christophe Massard</name><affiliation wicri:level="3"><nlm:affiliation>Gustave Roussy, Université Paris-Saclay, Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Gustave Roussy, Université Paris-Saclay, Villejuif</wicri:regionArea><placeName><settlement type="city">Villejuif</settlement></placeName></affiliation></author><author><name sortKey="Portera, Chia" sort="Portera, Chia" uniqKey="Portera C" first="Chia" last="Portera">Chia Portera</name><affiliation wicri:level="2"><nlm:affiliation>Covance Inc., Princeton, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Covance Inc., Princeton, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Saini, Monika Lamba" sort="Saini, Monika Lamba" uniqKey="Saini M" first="Monika Lamba" last="Saini">Monika Lamba Saini</name><affiliation wicri:level="1"><nlm:affiliation>HistoGeneX, Antwerp, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>HistoGeneX, Antwerp</wicri:regionArea><wicri:noRegion>Antwerp</wicri:noRegion></affiliation></author><author><name sortKey="Singh, Brajendra Prasad" sort="Singh, Brajendra Prasad" uniqKey="Singh B" first="Brajendra Prasad" last="Singh">Brajendra Prasad Singh</name><affiliation wicri:level="1"><nlm:affiliation>Max Smart Super Speciality Hospital, Saket, New Delhi, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Max Smart Super Speciality Hospital, Saket, New Delhi</wicri:regionArea><wicri:noRegion>New Delhi</wicri:noRegion></affiliation></author><author><name sortKey="Venkitaraman, Ramachandran" sort="Venkitaraman, Ramachandran" uniqKey="Venkitaraman R" first="Ramachandran" last="Venkitaraman">Ramachandran Venkitaraman</name><affiliation wicri:level="1"><nlm:affiliation>East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>East Suffolk and North Essex NHS Foundation Trust, Ipswich</wicri:regionArea><wicri:noRegion>Ipswich</wicri:noRegion></affiliation></author><author><name sortKey="Mcnally, Richard" sort="Mcnally, Richard" uniqKey="Mcnally R" first="Richard" last="Mcnally">Richard Mcnally</name><affiliation wicri:level="2"><nlm:affiliation>Covance Inc., Princeton, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Covance Inc., Princeton, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Leone, Manuela" sort="Leone, Manuela" uniqKey="Leone M" first="Manuela" last="Leone">Manuela Leone</name><affiliation wicri:level="2"><nlm:affiliation>Covance Inc., Princeton, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Covance Inc., Princeton, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Grande, Enrique" sort="Grande, Enrique" uniqKey="Grande E" first="Enrique" last="Grande">Enrique Grande</name><affiliation wicri:level="3"><nlm:affiliation>MD Anderson Cancer Center Madrid, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>MD Anderson Cancer Center Madrid, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Gupta, Sudeep" sort="Gupta, Sudeep" uniqKey="Gupta S" first="Sudeep" last="Gupta">Sudeep Gupta</name><affiliation wicri:level="1"><nlm:affiliation>Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Tata Memorial Centre, Homi Bhabha National Institute, Mumbai</wicri:regionArea><wicri:noRegion>Mumbai</wicri:noRegion></affiliation></author></analytic><series><title level="j">Oncology and therapy</title><idno type="eISSN">2366-1089</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The coronavirus disease-2019 (COVID-19) pandemic has had a significant impact on patients with underlying malignancy. In this article, we summarize emerging data related to patients with cancer and COVID-19. Among patients with COVID-19, a higher proportion have an underlying diagnosis of cancer than seen in the general population. Also, patients with malignancy are likely to be more vulnerable than the general population to contracting COVID-19. Mortality is significantly higher in patients with both cancer and COVID-19 compared with the overall COVID-19-positive population. The early months of the pandemic saw a decrease in cancer screening and diagnosis, as well as postponement of standard treatments, which could lead to excess deaths from cancer in the future.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32749634</PMID><DateRevised><Year>2020</Year><Month>09</Month><Day>09</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2366-1089</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Aug</Month><Day>04</Day></PubDate></JournalIssue><Title>Oncology and therapy</Title><ISOAbbreviation>Oncol Ther</ISOAbbreviation></Journal><ArticleTitle>Cancer Treatment and Research During the COVID-19 Pandemic: Experience of the First 6 Months.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1007/s40487-020-00124-2</ELocationID><Abstract><AbstractText>The coronavirus disease-2019 (COVID-19) pandemic has had a significant impact on patients with underlying malignancy. In this article, we summarize emerging data related to patients with cancer and COVID-19. Among patients with COVID-19, a higher proportion have an underlying diagnosis of cancer than seen in the general population. Also, patients with malignancy are likely to be more vulnerable than the general population to contracting COVID-19. Mortality is significantly higher in patients with both cancer and COVID-19 compared with the overall COVID-19-positive population. The early months of the pandemic saw a decrease in cancer screening and diagnosis, as well as postponement of standard treatments, which could lead to excess deaths from cancer in the future.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>de Las Heras</LastName><ForeName>Begoña</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Covance Inc., Princeton, NJ, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Madrid Medical Doctors Association, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Saini</LastName><ForeName>Kamal S</ForeName><Initials>KS</Initials><Identifier Source="ORCID">http://orcid.org/0000-0001-6301-3309</Identifier><AffiliationInfo><Affiliation>Covance Inc., Princeton, NJ, USA. kamalveer.saini@covance.com.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK. kamalveer.saini@covance.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Boyle</LastName><ForeName>Frances</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Mater Hospital, Sydney, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ades</LastName><ForeName>Felipe</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Hospital Alemão Oswaldo Cruz, São Paulo, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Azambuja</LastName><ForeName>Evandro</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Institut Jules Bordet, Brussels, Belgium.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Université Libre de Bruxelles (U.L.B.), Brussels, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bozovic-Spasojevic</LastName><ForeName>Ivana</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Romano</LastName><ForeName>Marco</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Covance Inc., Princeton, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Capelan</LastName><ForeName>Marta</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Vall d'Hebron University Hospital, Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prasad</LastName><ForeName>Rajeev</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pattu</LastName><ForeName>Pugazhenthi</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Massard</LastName><ForeName>Christophe</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Gustave Roussy, Université Paris-Saclay, Villejuif, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Portera</LastName><ForeName>Chia</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Covance Inc., Princeton, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Saini</LastName><ForeName>Monika Lamba</ForeName><Initials>ML</Initials><AffiliationInfo><Affiliation>HistoGeneX, Antwerp, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Singh</LastName><ForeName>Brajendra Prasad</ForeName><Initials>BP</Initials><AffiliationInfo><Affiliation>Max Smart Super Speciality Hospital, Saket, New Delhi, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Venkitaraman</LastName><ForeName>Ramachandran</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McNally</LastName><ForeName>Richard</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Covance Inc., Princeton, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Leone</LastName><ForeName>Manuela</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Covance Inc., Princeton, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grande</LastName><ForeName>Enrique</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>MD Anderson Cancer Center Madrid, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gupta</LastName><ForeName>Sudeep</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>08</Month><Day>04</Day></ArticleDate></Article><MedlineJournalInfo><Country>New Zealand</Country><MedlineTA>Oncol Ther</MedlineTA><NlmUniqueID>101677510</NlmUniqueID><ISSNLinking>2366-1089</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">Cancer</Keyword><Keyword MajorTopicYN="N">Coronavirus</Keyword><Keyword MajorTopicYN="N">Immuno-oncology</Keyword><Keyword MajorTopicYN="N">Malignancy</Keyword><Keyword MajorTopicYN="N">Mortality</Keyword><Keyword MajorTopicYN="N">Pandemic</Keyword><Keyword MajorTopicYN="N">Risk</Keyword><Keyword MajorTopicYN="N">SARS-CoV-2</Keyword><Keyword MajorTopicYN="N">Therapy</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>07</Month><Day>13</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>8</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>8</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>8</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32749634</ArticleId><ArticleId IdType="doi">10.1007/s40487-020-00124-2</ArticleId><ArticleId IdType="pii">10.1007/s40487-020-00124-2</ArticleId><ArticleId IdType="pmc">PMC7402077</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Ecancermedicalscience. 2020 May 18;14:1047</Citation><ArticleIdList><ArticleId 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Leone</name><name sortKey="Mcnally, Richard" sort="Mcnally, Richard" uniqKey="Mcnally R" first="Richard" last="Mcnally">Richard Mcnally</name><name sortKey="Portera, Chia" sort="Portera, Chia" uniqKey="Portera C" first="Chia" last="Portera">Chia Portera</name><name sortKey="Romano, Marco" sort="Romano, Marco" uniqKey="Romano M" first="Marco" last="Romano">Marco Romano</name><name sortKey="Saini, Kamal S" sort="Saini, Kamal S" uniqKey="Saini K" first="Kamal S" last="Saini">Kamal S. Saini</name></country><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="De Las Heras, Bego A" sort="De Las Heras, Bego A" uniqKey="De Las Heras B" first="Bego A" last="De Las Heras">Bego A De Las Heras</name></region><name sortKey="Capelan, Marta" sort="Capelan, Marta" uniqKey="Capelan M" first="Marta" last="Capelan">Marta Capelan</name><name sortKey="Grande, Enrique" sort="Grande, Enrique" uniqKey="Grande E" first="Enrique" last="Grande">Enrique Grande</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Saini, Kamal S" sort="Saini, Kamal S" uniqKey="Saini K" first="Kamal S" last="Saini">Kamal S. Saini</name></noRegion><name sortKey="Pattu, Pugazhenthi" sort="Pattu, Pugazhenthi" uniqKey="Pattu P" first="Pugazhenthi" last="Pattu">Pugazhenthi Pattu</name><name sortKey="Prasad, Rajeev" sort="Prasad, Rajeev" uniqKey="Prasad R" first="Rajeev" last="Prasad">Rajeev Prasad</name><name sortKey="Venkitaraman, Ramachandran" sort="Venkitaraman, Ramachandran" uniqKey="Venkitaraman R" first="Ramachandran" last="Venkitaraman">Ramachandran Venkitaraman</name></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Boyle, Frances" sort="Boyle, Frances" uniqKey="Boyle F" first="Frances" last="Boyle">Frances Boyle</name></region></country><country name="Brésil"><region name="État de São Paulo"><name sortKey="Ades, Felipe" sort="Ades, Felipe" uniqKey="Ades F" first="Felipe" last="Ades">Felipe Ades</name></region></country><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="De Azambuja, Evandro" sort="De Azambuja, Evandro" uniqKey="De Azambuja E" first="Evandro" last="De Azambuja">Evandro De Azambuja</name></region><name sortKey="De Azambuja, Evandro" sort="De Azambuja, Evandro" uniqKey="De Azambuja E" first="Evandro" last="De Azambuja">Evandro De Azambuja</name><name sortKey="Saini, Monika Lamba" sort="Saini, Monika Lamba" uniqKey="Saini M" first="Monika Lamba" last="Saini">Monika Lamba Saini</name></country><country name="Serbie"><noRegion><name sortKey="Bozovic Spasojevic, Ivana" sort="Bozovic Spasojevic, Ivana" uniqKey="Bozovic Spasojevic I" first="Ivana" last="Bozovic-Spasojevic">Ivana Bozovic-Spasojevic</name></noRegion></country><country name="France"><noRegion><name sortKey="Massard, Christophe" sort="Massard, Christophe" uniqKey="Massard C" first="Christophe" last="Massard">Christophe Massard</name></noRegion></country><country name="Inde"><noRegion><name sortKey="Singh, Brajendra Prasad" sort="Singh, Brajendra Prasad" uniqKey="Singh B" first="Brajendra Prasad" last="Singh">Brajendra Prasad Singh</name></noRegion><name sortKey="Gupta, Sudeep" sort="Gupta, Sudeep" uniqKey="Gupta S" first="Sudeep" last="Gupta">Sudeep Gupta</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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